Lapatinib is a medication used to treat certain types of breast cancer and is marketed under the brand name Tykerb. It is specifically used for cancers that are HER2-positive, a designation indicating that the cancer cells have a high level of the HER2 protein, which promotes cancer cell growth.
Mechanism of Action
- Tyrosine Kinase Inhibitor: lapatinib price philippines works by inhibiting the activity of tyrosine kinases, which are enzymes involved in the signaling pathways that control cell growth and division. Specifically, it targets the HER2 and EGFR (epidermal growth factor receptor) pathways, which are often overactive in certain cancer cells.
Administration
- Form: Lapatinib is taken orally in the form of tablets.
- Dosage: The typical dose is 1,250 mg once daily, often in combination with other medications like capecitabine or letrozole, depending on the specific treatment regimen.
Indications
- HER2-Positive Breast Cancer: Lapatinib is used to treat HER2-positive breast cancer, particularly in cases that are advanced or metastatic and have not responded to other treatments.
Benefits
- Efficacy: lapatinib price in india has been shown to help control the growth of HER2-positive breast cancer and can improve progression-free survival.
- Combination Therapy: When used in combination with other drugs, it can enhance the overall effectiveness of treatment.
Side Effects
Common side effects of lapatinib may include:
- Diarrhea
- Nausea
- Fatigue
- Rash
- Loss of appetite
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